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Connecting genetic risk factors to specific symptoms in autism

Genome wide association studies, genetic epidemiological investigations and numerous gene sequencing approaches have led to a growing appreciation of a genetic component to autism spectrum disorder...

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Transgenerational responses to nutrition

Heritability has been the focus of scientific research through the ages, with renewed interest following the advent of genomics and epigenetics. A key question yet to be comprehensively answered is...

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From canine genetics to human disease

Canine research is a growing and dynamic field, which not only informs veterinary practice and breeding but also provides insights into human disease. Addressing the breadth of findings this field has...

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A sperm’s tale: Mark Jobling on factoring in mutations in sperm donation

This article was written by Mark Jobling, professor of genetics at the University of Leicester, and originally published in Investigative Genetics.   Copenhagen is as flat as the proverbial pancake. A...

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Getting to grips with the genetics and genomics of Parkinson’s disease

The neurodegenerative condition, Parkinson’s disease, is largely sporadic however recent decades have seen our understanding of the genetics of this disease grow. Over twenty different genes have been...

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What exactly can genetics tell us about autism?

Though reports of autism stretch back through the centuries, it first took on its modern meaning around the 1940’s. The road to understanding the causes and underlying pathology of autism spectrum...

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Human-induced evolution in action

Salmon lice; (top) mature female with egg strings, (middle) mature female without egg stings, (bottom) immature louse. Image source: Wikimedia, Thomas Bjørkan Of the many characteristics humans...

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Focus on rare diseases: from skeletal dysplasia to Prader-Willi syndrome

Skeletal dysplasias, the eye disorders anopthalmia and micropthalmia, and Prader-Willi syndrome are all rare diseases that whilst perhaps neglected in the past due to their low prevalence, today form...

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How sweet it is: sugar metabolism networks in peach

A delicious summer peach is valued for its taste, but what controls the balance of sugars and acids that combine to make the fruit so sweet? Although the production and accumulation of individual...

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Tackling tomorrow’s GWAS with the latest software developments

The software application PLINK is one of the most widely used tools in bioinformatics, particularly for genome-wide association studies (GWAS), that look at genetic variants in different individuals to...

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